Consequences of Obesity Part 1: Diabetes and Cardiovascular Disease
Learning Objectives
After completion of this module students will be able to:
Explain why the prevalence of diabetes is of epidemic proportions.
Differentiate between Type 1 and Type 2 diabetes and their harmful effects on the body.
Describe ways to diagnose and treat diabetes.
Describe the relationship between obesity and cardiovascular disease.
Identify common cardiovascular diseases.
Describe different types of cholesterol and their effects on the body.
Key Concepts - Diabetes
Diabetes is a global epidemic that has increased dramatically in the last 10 years.
An estimated 1 in 3 people is expected to be diagnosed with the disease by 2050.
Glucose intolerance is characterized by abnormal blood sugars and utilization of carbohydrates. Glucose testing identifies individuals who are glucose intolerant.
Pathology of diabetes differs in Type 1 and Type 2
Diabetes complications are thought to be a “silent” killer.
Risk factors of diabetes may be non-modifiable such as race or gender or modifiable such as diet or exercise.
Key Concepts - Cardiovascular Disease
Cardiovascular disease (CVD) refers to any health problem that effects the heart or blood vessels.
There are three types of atherosclerosis: heart disease, stroke, and limb loss which are all caused by blockages of key arteries.
CVD is the leading cause of death for men and women. About 1 in 4 people will develop CVD. Someone dies from CVD every 34 seconds.
Bad (LDL) cholesterol can cause clogged and narrow arteries and prevent blood flow carrying nutrients and oxygen.
Metabolic syndrome and obesity doubles the risk of developing CVD.
Video Microlectures
Video: Diabetes
Dr. Nana Gletsu-Miller, Department of Nutrition Science, Purdue University
Video: Cardiovascular Disease
Dr. Kimberly K. Buhman, Department of Nutrition Science, Purdue University
Optional Readings
Look AHEAD Research Group. (2014). Eight-year weight losses with an intensive life
style intervention: the look AHEAD study. Obesity, 22, 5-13.
Shashaj, B., Bedogni, G., Graziani, M. P., Tozzi, A. E., DiCorpo, M. L., Morano, D., ... &
Manco, M. (2014). Origin of cardiovascular risk in overweight preschool children: a
cohort study of cardiometabolic risk factors at the onset of obesity. JAMA pediatrics,
168, 917-924.